Centrosomes are not essential for cell division in most animal cells, although they contribute to the efficiency of mitotic spindle assembly. Centrosome loss is tolerated surprisingly well in fly ...
Centrosomes are small structures in cells with many essential functions, including roles in cell signaling and in organizing a cell’s cytoskeleton. Centrosome dysfunction contributes to diseases like ...
The centrosome, consisting of a pair of centrioles and pericentriolar material (PCM), is the major microtubule-organizing centre (MTOC) of many eukaryotic cells. Centrosome duplication and MTOC ...
The cover for issue 26 of Oncotarget features Figure 6, "Mislocalization of IQGAP1-BRCA1 in human TNBC tumors phenocopies the dominant mutants and the TNBC cells," by Osman, et al. and reported that ...
A recent Cell Reports paper by the Oxenius group (IMB) demonstrates a function of targeted centrosome inheritance during CD8+ T cell division for the generation of memory precursor cells.
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