Early in the pain process, newly generated neurons in the dentate gyrus showed increased activity – suggesting the brain initially mounts a protective response to persistent pain. Over time, however, ...

Scientists have uncovered a brain mechanism that may explain why chronic pain leads to depression in some people but not ...

A new brain-imaging study has revealed how ketamine produces its fast antidepressant effects in people with treatment-resistant depression. Researchers tracked changes in a critical brain receptor ...

Depression is a mental health disorder characterized by a recurrent or persistent sadness and a loss of interest in activities that were previously deemed pleasurable, sometimes accompanied by changes ...

New research published in Drug and Alcohol Dependence provides evidence that experiencing depression symptoms alongside ...

A study reveals that changes in the hippocampus, a key brain area, may determine why some individuals with chronic pain ...

Changes to one's hippocampus, the brain's memory centre, in response to prolonged pain could be an important factor for why ...

Events during childhood may continue to affect our emotions as adults. There has been plenty of evidence, for example, that people who experienced childhood trauma are more vulnerable to depression.

It's widely recognized that psychiatric conditions like depression and anxiety disorders are based in the brain. Scientists have even started to discover which brain areas are involved in different ...

Scientists have uncovered a brain mechanism that may explain why chronic pain leads to depression in some people but not ...