TNBCs rely on fatty acid oxidization (FAO) to fuel tumor growth by breaking down surrounding adipose tissue through lipolysis. Gap junctions, particularly involving GJB3 and connexin 31 (Cx31), ...

Researchers at The Hong Kong University of Science and Technology (HKUST) have developed CarGAP, a chemo-optogenetic tool that uses vitamin B₁₂ and green light to precisely control gap junctions, the ...

Patients with triple-negative breast cancer (TNBC) have more aggressive, invasive tumors and fewer treatment options than other kinds of breast cancers. TNBC tumors use fatty acid oxidation as a key ...

UCSF scientists caught cancer cells in the act of breaking into fat cells and releasing their fat. The energy heist seems to be critical for the growth of deadly breast cancer. The study appears in ...